Dartmouth Digital Library Program

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Synthetic and mechanistic studies in tetrapyrrole chemistry.
Tetrapyrroles -- Synthesis. Tetrapyrroles -- Mechanism of action. Transition metal catalysts.
Previous studies have shown that the mucosal immune system is present in the female reproductive tract and under hormonal control. With the recognition that underlying stromal cells regulate epithelial cell function and hormonal responsiveness,...
Dartmouth Dissertations

Molecular, cellular, and physiological characterization of the insulin receptor substrate 4.
Protein-tyrosine kinase. ; Insulin -- Receptors.
Upon activation by binding of insulin, the insulin receptor tyrosine kinase phosphorylates a group of proteins known as the insulin receptor substrates (IRS's). The tyrosine phosphorylated IRS's then act as docking/effector molecules for SH2...
Dartmouth Dissertations

Stratigraphy, structure, and petrology of the Peterborough 15-minute quadrangle, New Hampshire; and Part II. Graphite textural and isotopic variations in plutonic rocks, south-central New Hampshire.
Geology -- New Hampshire -- Peterborough Quadrangle. Geology Stratigraphic. Geology.
Dartmouth Dissertations

Stable isotope paleoclimate studies in the western Basin and Range and greater Yellowstone Region.
Orogeny -- Sierra Nevada (California and Nevada). ; Paleoclimatology -- Sierra Nevada (California and Nevada). ; Paleoclimatology -- Montana. ; Paleoclimatology -- Holocene. ; Metamorphism (Geology) -- Pakistan -- Nanga Parbat.
Dartmouth Dissertations

Geographic variation in the supply and use of inpatient post-acute care and its association with orthopedic surgery.
Hospitals -- After care -- United States. Medicare beneficiaries -- Hospital care -- Costs. Geriatric orthopedics -- Economic aspects. Health services accessibility -- United States. After care -- supply & distribution -- United States.
Dartmouth Dissertations

Using theory to predict phase behaviour in liquids, copolymer melts, and ultrathin polymer films / by Nicholas B. Tito.
Thermodynamics, and the classic balance between entropy and enthalpy, provides a proverbial zoo of exotic phase behaviour that chemists can harness to create new materials out of simple liquids and polymers. The diversity of self-assembling...
Dartmouth Dissertations

Isolation and characterization of QCR9 the nuclear gene encoding the 7.3 kDa subunit 9 of the Saccharomyces cerevisiae bc1 complex.
Oxidoreductases. Cytochrome c. Saccharomyces cerevisiae.
Dartmouth Dissertations

Kinetic characterization of metabolism and antibody production of a hybridoma cell line in high density homogeneous perfusion culture.
Hybridomas -- Metabolism. Hybridomas -- Growth. Cultures (Biology).
Dartmouth Dissertations

An experimental study of the propagation and dispersion of internal atmospheric gravity waves.
Gravity waves. Ionosphere.
Dartmouth Dissertations

Directional recrystallization of copper and nickel.
Recrystallization (Metallurgy). ; Copper -- Thermomechanical properties. ; Nickel -- Thermomechanical properties. ; Metal crystals -- Growth. ; Microstructure. Annealing of metals. Recrystallization (Metallurgy) -- Computer simulation.
The effects of process parameters on the microstructural and textural evolution during directional recrystallization processing were investigated. Microstructural evolution during primary directional recrystallization of 80% cold-rolled, single...
Dartmouth Dissertations

Inf2-formin that polymerizes and depolymerizes actin on endoplasmic reticulum.
Actin. Microfilament proteins. Polymerization. Endoplasmic reticulum.
Dartmouth Dissertations

Host-epibiont population dynamics.
Daphnia pulex -- Ecology. ; Epibiosis. Host-parasite relationships. ; Euglenoids -- Ecology.
Regulatory linkage between epibiotic organisms and their host zooplankton populations is one of the least understood topics in zooplankton biology, despite the likely importance of epibionts to pelagic communities. These laboratory studies with...
Dartmouth Dissertations

Nonstigmatized individuals' reactions to the acknowledgment and valuation of a stigma by overweight individuals and physically disabled individuals.
Overweight persons -- Attitudes. ; People with disabilities -- Attitudes. ; Obesity -- Public opinion. ; Stigma (Social psychology). ; Self-presentation.
In the last few years, a new perspective on the management of obesity has emerged. Instead of focusing on dieting and weight loss efforts, the new approach focuses on size acceptance. The concept of positively accepting one's deviant features has...
Dartmouth Dissertations

Syntheses of transition metal complexes containing fluorinated ligands.
Ruthenium compounds -- Synthesis. ; Organorhodium compounds -- Synthesis. ; Organometallic chemistry.
Dartmouth Dissertations

Morphological, semantic and formal relationships in the organisation of the mental lexicon.
Learning, Psychology of. ; Psycholinguistics.
Dartmouth Dissertations

Intrinsic integral representations and boundary theory for superharmonic measures of a random walk.
Random walks (Mathematics). ; Integrals.
Dartmouth Dissertations

Investigation of ER-Golgi membrane proteins influencing COPII tethering and fusion / by Indrani Mukherjee
Protein secretion is executed by the secretory pathway, which involves the delivery of membrane and soluble secretory proteins in vesicle intermediates that capture newly-synthesized proteins assembled in the endoplasmic reticulum (ER) and then...
Dartmouth Dissertations

I. Reactivity of electron deficient indoles toward nucleophiles, Diels-Alder reactions and dipolar cycloadditions; II. Synthesis of pyrrolo[3,4-b]indoles.
Indole -- Synthesis. Indole -- Reactivity. Pyrroles. Diels-Alder reaction.
Earlier in our laboratory, a facile synthesis of the 2- and 3-nitroindoles was realized. These compounds showed promise as powerful intermediates in the synthesis of novel structures and natural products. The reactivity of 2- and 3-nitroindoles...
Dartmouth Dissertations

NPC1-mediated trafficking of intracellular cholesterol.
Cholesterol -- Physiological transport. Cholesterol -- Genetic aspects. Cholesterol -- Metabolism. Genetic disorders -- Molecular aspects.
Niemann-Pick type C (NPC) is a neurovisceral disease that causes intracellular accumulation of cholesterol and other lipids. The exact mechanism how the defects in cholesterol trafficking pathways result in the progressive neurological damage is...
Dartmouth Dissertations

Observation of changing information sources.
Information resources management -- Mathematical models. ; Database management -- Methodology. ; Change. ; World Wide Web.
Many modern information management tasks consist of an observer that must maintain current knowledge of a collection of changing information. The goal of this observer is to maintain acceptably accurate state estimates given limited observation...
Dartmouth Dissertations

Ionic basis of neuronal CO²/H+ chemosensitivity in the pulmonate snail, Helix aspersa.
Hypercapnia -- Regulation. ; Carbon dioxide -- Physiological effect. ; Carbon dioxide in the body. ; Brown garden snail -- Respiration. ; Potassium channels.
After more than 150 years of studying the respiratory effects of hypercapnia, the intrinsic neuronal mechanism by which carbon dioxide (CO²) stimulates electrical excitability of respiratory neurons, and hence respiratory drive, is still...
Dartmouth Dissertations

In vitro reconstitution of exocytosis from sea urchin egg plasma membrane and isolated secretory vesicles.
Sea urchins -- Cytology.
Dartmouth Dissertations

Constraints on the total binding masses of three double clusters of galaxies.
Galaxies -- Clusters -- Mathematical models. ; Cosmology -- Mathematical models.
Dartmouth Dissertations

The regulation of AMP-activated protein kinase (AMPK) in an insulinoma cell line, adipocytes and muscle.
Protein kinases. ; Adenylic acid. ; Islands of Langerhans -- Tumors. ; Fat cells. ; Muscle cells. ; Adenoviruses.
Dartmouth Dissertations

X-ray topography of freshwater ice.
Ice crystals -- Radiography. ; Dislocations in crystals. ; Synchrotron radiation.
Dartmouth Dissertations

Part I, syntheses and studies of perfluorotropylium ion and perfluorotropone Part II, synthesis of octachloroazulene.
Fluorine compounds -- Synthesis. ; Chlorides -- Synthesis. ; Halogen compounds -- Synthesis.
Dartmouth Dissertations

Computations of wall-bounded two-dimensional turbulence.
Turbulence. ; Navier-Stokes equations -- Numerical solutions. ; Galerkin methods. ; Boundary layer -- Mathematical models. ; Viscous flow -- Mathematical models.
Dartmouth Dissertations

Fragmentation of hemicellulose during pretreatment: the predicted effect of sulfuric acid on sugar release selectivity.
Hemicellulose -- Biodegradation. Lignin -- Biodegradation. Biomass chemicals. Sulfuric acid. Hydrolysis.
Dartmouth Dissertations

Molecular analysis of mannose-sensitive hemagglutinin formation and toxin secretion by Vibrio cholerae.
Vibrio cholerae -- Molecular genetics. ; Hemagglutinin -- Analysis. ; Peptidase -- Pathophysiology.
The mannose-sensitive hemagglutinin (MSHA) of Vibrio cholerae is a member of the family of type 4 pili. Type 4 pili expressed on the surface of a number of Gram-negative bacteria are often required for host colonization. MSHA is specifically...
Dartmouth Dissertations

The biophysical characterization of the interaction of XPA and the minimal DNA binding domain, XPA-MF122, with a mitomycin C-DNA interstrand crosslink.
Mitomycin C -- Mechanism of action. ; Xeroderma pigmentosum. ; DNA -- Effect of mitomycin C on. ; DNA-protein interactions -- Effect of mitomycin C on. ; DNA repair. ; Arsenic -- Physiological effect. ; Cadmium -- Physiological effect.
Despite the fact that numerous chemically and structurally diverse DNA lesions are repaired by nucleotide excision repair (NER), the mechanism of the interaction of XPA with damaged DNA is not well characterized. The overall goal of this study was...
Dartmouth Dissertations

Extending the spatial and temporal applications of the U[superscript K][subscript 37] index as a marine paleotemperature proxy.
Marine sediments -- Analysis -- Chesapeake Bay (Maryland and Virginia). ; Marine sediments -- Analysis -- South China Sea. ; Paleoclimatology -- Chesapeake Bay (Maryland and Virginia). ; Paleoclimatology -- South China Sea. ; Paleoclimatology --...
Dartmouth Dissertations

Dose dependent effects of sodium arsenite on NF-κB and interleukin-8 in bronchial epithelial cells.
Epithelial cells. ; NF-kappa B (DNA-binding protein). ; Interleukin-8. ; Arsenic compounds -- Physiological effect.
Dartmouth Dissertations

Versatile 2-lithioindoles, syntheses and Diels-Alder reactions of pyrrolo[3,4-b]indoles.
Indole alkaloids -- Synthesis. Diels-Alder reaction.
An efficient synthetic approach to both 2-acyl-1-(substituted)indoles and 2-nitro-1-(substituted)indoles by reaction of 2-lithio-1-(substituted)indoles with appropriate electrophiles is presented. Inverse quenching of 2-lithioindoles 5 and 208 with...
Dartmouth Dissertations

Biophysical and ligand-binding characterization of the interleukin-2 receptor ß-subunit ectodomain.
Interleukin-2. ; T cells -- Receptors. ; Ligand binding (Biochemistry).
Dartmouth Dissertations

A rheological investigation of living cytoplasm.
Rheology (Biology). ; Cytoplasm.
Dartmouth Dissertations

Differentiating and anti-inflammatory activities of the triterpenoid, CDDO: interactions with transcription factors PPARγ and NF-κ B.
Triterpenoid saponins -- Physiology. ; Cell receptors. ; Receptor-ligand complexes. ; NF-kappa B (DNA-binding protein). ; Peroxisomes. ; Nucleophilic reactions. ; Dithiole.
Dartmouth Dissertations

Studies on the basis of the toxicity of aliphatic organonitriles.
Nitriles -- Toxicology. ; Polyamines.
Dartmouth Dissertations

Brittle-ductile transition in intermetallic compounds, Ni[subscript 3]Ga and Ni[subscript 3]A1.
Nickel alloys -- Brittleness. ; Nickel alloys -- Ductility. ; Nickel alloys -- Fracture.
Dartmouth Dissertations

Effects of selenium deficiency on deiodinase expression and thyroid hormone economy in the rat during development.
Thyroid hormones -- Physiological effect. ; Selenium -- Physiological effect. ; Thyroid hormones -- Synthesis.
The iodothyronine deiodinases, D1, D2, and D3, play a crucial role in determining the circulating and intracellular levels of active and inactive thyroid hormone (TH), and thus have a major effect on TH action during development and adulthood. The...
Dartmouth Dissertations

Isolation and characterization of two distinct mutations affecting cholesteryl ester synthesis in mammalian cells.
Cholesterol. ; Esters. ; Mammals -- Cytology. ; Cell metabolism.
Dartmouth Dissertations

Intracellular cholesterol trafficking in CHO cells defective in NPC1.
Cholesterol -- Physiological transport. ; Cholesterol -- Genetic aspects.
Cholesterol is essential for the survival of all mammalian cells. Mammalian cells obtain cholesterol via two pathways: it can be endogenously synthesized in the endoplasmic reticulum, or it can be obtained from exogenous sources, mainly through the...
Dartmouth Dissertations

Cellular concrete and its continuous manufacture.
Lightweight concrete.
Dartmouth Dissertations

Natural image statistics for digital image forensics.
Image processing -- Statistical methods. Image processing -- Digital techniques. Images
We describe a set of natural image statistics that are built upon two multi-scale image decompositions, the quadrature mirror filter pyramid decomposition and the local angular harmonic decomposition. These image statistics consist of first- and...
Dartmouth Dissertations

The effects of Niemann-Pick type C disease on the development of Purkinje cell form and function.
Purkinje cells. Neurons -- Physiology. Neurons -- Growth. Developmental neurobiology. Nerve growth factor. Niemann-Pick Diseases. Central Nervous System -- growth & development.
Dartmouth Dissertations

Quality control of solid dielectric cable.
Electric cables. ; Dielectrics.
Dartmouth Dissertations

The role of tocopherol (vitamin E) in rotifer ecology.
Rotifera. ; Vitamin E.
Dartmouth Dissertations

Determinants of competitive outcome between rotifers and cladocerans.
Cladocera. ; Rotifera. ; Competition (Biology).
Dartmouth Dissertations

Mobile agent planning problems.
Mobile agents (Computer software). ; Electronic data processing -- Distributed processing. ; Sequential processing (Computer science) -- Mathematical models.
Mobile agents have received much attention recently as a way to efficiently access distributed resources in a low bandwidth network. Planning allows mobile agents to make the best use of the available resources. This thesis studies several planning...
Dartmouth Dissertations

Functional and structural relationship among glycerophosphate dehydrogenase isozymes and allozymes from Drosophila melanogaster.
Drosophila melanogaster.
Dartmouth Dissertations

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