Dartmouth Digital Library Program

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Links and regulatory loops between phospholipase C activity and colonization by the O2-responsive regulator Anr in Pseudomonas aeruginosa / by Angelyca A. Jackson.
Pseudomonas aeruginosa is a virulent opportunistic pathogen that is frequently cultured from infectious sites, and is estimated to cause ~12% of nosocomial infections worldwide [1]. P. aeruginosa infections occur in a majority of adults with the...
Dartmouth Dissertations

Sexual selection and sexual conflict in Anolis lizards : from molecules to populations / by M. Catherine Duryea.
Sexual selection is a driver of biodiversity and creates spectacular forms of variation. However, only recently have we begun to understand how this variation operates on the postcopulatory level and how cryptic mechanisms affect male-male...
Dartmouth Dissertations

The effects of food resources and conspecifics on the foraging, survivorship, and reproduction of the omnivorous copepod Epischura lacustris
Epischura; Epischura -- Food
Dartmouth Dissertations

Microwave imaging for 2-D electrical property distribution profiling.
Image reconstruction. Microwave imaging. Microwave imaging -- Instruments -- Design and construction. Microwave imaging in medicine.
Dartmouth Dissertations

Quantitative analysis of polycyclic aromatic hydrocarbons in airborne particulates: Semiquantitative determination of organic material in woodsmoke.
Hydrocarbons -- Analysis. Smoke -- Analysis.
Dartmouth Dissertations

Biochemical studies of prion composition and conversion.
Prions. Proteins -- Conformation. Prions -- physiology. Prions -- genetics.
Prion diseases are fatal neurodegenerative disorders which affect a variety of different animal species including humans. The central pathogenic event underlying prion diseases is the conformational conversion of the cellular prion protein (PrP C )...
Dartmouth Dissertations

Demography and movement of migratory wildebeest (Connochaetes taurinus) in northern Tanzania
Gnus -- Tanzania -- Geographical distribution. ; Gnus -- Migration -- Tanzania.
Dartmouth Dissertations

Nonstigmatized individuals' reactions to the acknowledgment and valuation of a stigma by overweight individuals and physically disabled individuals.
Overweight persons -- Attitudes. ; People with disabilities -- Attitudes. ; Obesity -- Public opinion. ; Stigma (Social psychology). ; Self-presentation.
In the last few years, a new perspective on the management of obesity has emerged. Instead of focusing on dieting and weight loss efforts, the new approach focuses on size acceptance. The concept of positively accepting one's deviant features has...
Dartmouth Dissertations

Cinder cone distribution described using cluster analysis and two-dimensional Fourier analysis in the central Transmexican Volcanic Belt, Mexico, and in SE Guatemala and NW El Salvador.
Volcanism -- Mexico. ; Volcanism -- Guatemala. ; Volcanism -- El Salvador. ; Cluster analysis.
Dartmouth Dissertations

Ionic and mechanical responses of the rat brain to acute dilutional hyponatremia.
Brain -- Physiology. ; Hyponatremia.; Rats.
Dartmouth Dissertations

The influence of spatial expectancy on spatial discriminability in single- and multiple-element displays.
Visual discrimination. ; Visual perception. ; Information display systems -- Psychological aspects.
Dartmouth Dissertations

Novel approaches to targeting innate immunity for cancer immunotherapy / by Patrick H. Lizotte
Many kinds of cancer, and almost universally metastatic cancer, are refractory to treatment by conventional methods: surgery, radiation, and non-specific cytotoxic chemotherapy. The dawn of the age of personalized medicine presaged 15 years ago...
Dartmouth Dissertations

Torsional movements in the large free living amoebae.
Amoeba. ; Torsion.
Dartmouth Dissertations

Effects of particles on anelasticity, creep and microstructural evolution of granular ice.
Ice mechanics. Internal friction. Ice -- Creep. Particles. Dislocations in crystals.
This work studied the effects of silt-sized particles on the mechanical properties and microstructures of laboratory-grown granular ice from -20¬∞C to -2¬∞C. Experimental findings show that such particles significantly affect the...
Dartmouth Dissertations

Monitoring late radiation damage in normal muscle tissue with electrical impedance spectroscopy.
Muscle cells -- Effect of radiation on. ; Radiation -- Physiological effect. ; Electrical impedance tomography. ; Spectroscopic imaging.
Dartmouth Dissertations

Bimolecular and intramolecular fluorescence quenching of an amine by a nitrile: Solution properties and chain structure of poly(1-olefin sulfone)s.
Amines. ; Nitriles. ; Sulfones. ; Alkenes.
Dartmouth Dissertations

Differentiating and anti-inflammatory activities of the triterpenoid, CDDO: interactions with transcription factors PPARγ and NF-κ B.
Triterpenoid saponins -- Physiology. ; Cell receptors. ; Receptor-ligand complexes. ; NF-kappa B (DNA-binding protein). ; Peroxisomes. ; Nucleophilic reactions. ; Dithiole.
Dartmouth Dissertations

Stereopsis-guided brain shift compensation.
Three-dimensional imaging in medicine -- Mathematical models. Intraoperative monitoring. Cerebral cortex -- Imaging. Computer vision. Space perception.
Brain deformation models have proven to be a powerful tool in compensating for soft tissue deformation during image-guided neurosurgery. The accuracy of these models can be improved by incorporating intraoperative measurements of brain motion. We...
Dartmouth Dissertations

Metamorphism in east central Vermont.
Metamorphism (Geology) -- Vermont. ; Nappes (Geology) -- Vermont.
Dartmouth Dissertations

Expression of sporophytic and gametophytic storage proteins in the quillwort.
Lycopodiaceae -- Spores. ; Club mosses -- Spores. ; Generations Alternating.
Dartmouth Dissertations

Functional analysis of cell cycle genes by genome-wide expression data and meta-analysis of RNAi screens.
Cell cycle -- Regulation. ; Genetic regulation. ; Small interfering RNA. ; Spindle (Cell division). ; Epithelial cells -- Genetic aspects. ; Mammary glands -- Cytology. ; Cell lines. ; Cell Cycle -- genetics. ; Genes cdc. ; RNA Interference. ;...
Successful traversal of the cell division cycle is paramount for maintaining a cell's genomic integrity and fitness. To ensure the faithful replication and segregation of the genome, cellular components, and cytoplasm, eukaryotes have evolved a...
Dartmouth Dissertations

Natural image statistics for digital image forensics.
Image processing -- Statistical methods. Image processing -- Digital techniques. Images
We describe a set of natural image statistics that are built upon two multi-scale image decompositions, the quadrature mirror filter pyramid decomposition and the local angular harmonic decomposition. These image statistics consist of first- and...
Dartmouth Dissertations

Studies on the role of the SH2 domain-containing phosphotyrosine phosphatase, PTP2C, in insulin signaling.
Insulin -- Receptors. ; Phosphatases. ; Phosphorylation. ; Cellular control mechanisms.
Dartmouth Dissertations

Isolation and characterization of Chinese hamster ovary cell lines possessing abnormal LDL-derived cholesterol trafficking.
Cholesterol. ; Mutation (Biology). ; Low density lipoproteins. ; Cell lines.
Dartmouth Dissertations

Regulation of constitutive MMP-1 expression by the ERK signaling cascade in tumor cells.
Metalloproteinases -- Genetic aspects. ; Metalloproteinases -- Pathophysiology. ; Cellular signal transduction. ; Breast -- Cancer -- Genetic aspects. ; Protein kinases -- Genetic aspects. ; Extracellular matrix proteins. ; Extracellular...
Matrix metalloproteinase-1 (MMP-1) expression is controlled by the mitogen activated protein kinase (MAPK) pathway(s) via the activity of activator protein-1 (AP-1) and polyoma enhancing activity-3/E26 virus (PEA3/ETS) transcription factors through...
Dartmouth Dissertations

Iron uptake in Arabidopsis thaliana.
Arabidopsis thaliana. ; Iron -- Metabolism. ; Growth (Plants). ; Plants -- Effect of iron on.
Dartmouth Dissertations

The relationship between habitat and performance of age-0 Atlantic salmon.
Atlantic salmon -- Habitat. ; Atlantic salmon -- Food. ; Atlantic salmon -- Growth. ; Atlantic salmon -- Development.
In this study, I examined the interactive effects of prey and physical habitat on foraging, habitat selection, growth, and survival of age-0 Atlantic salmon, Salmo salar. I combined field observations of salmon behavior, surveys of habitat and prey...
Dartmouth Dissertations

Role of the mixed lineage leukemia proto-oncogene in sustaining hematopoiesis.
Proto-oncogenes. Hematopoietic stem cells -- Genetic aspects. Leukemia -- Genetic aspects.
The Mixed Lineage Leukemia ( Mll ) gene is essential for embryonic hematopoietic stem cell (HSC) development but its role during adult hematopoiesis is unknown. Using a Mx1-Cre inducible knockout model, we demonstrate that Mll is essential for the...
Dartmouth Dissertations

Interspecific interactions and population dynamics of the Southern pine beetle.
Southern pine beetle -- Ecology. Mutualism (Biology). Commensalism.
A challenge for ecologists is to identify and understand the mechanisms that produce population behaviors in nature. This is particularly difficult in complex communities that comprise of tightly linked multivoltine organisms that are...
Dartmouth Dissertations

The molecular evolution of the Drosophila neurogenic ectodermal enhancers.
Drosophila -- Genetics. Transcription factors. DNA-protein interactions. Genetic transcription -- Regulation. Evolutionary genetics.
The control of gene expression is central to developmental biology, pattern formation, and phenotypic evolution. Enhancers are a class of regulatory DNAs that control when and where genes are turned ON or OFF. This highly regulated process is...
Dartmouth Dissertations

The evolution of metazoan microRNA genes and the advent of vertebrate complexity
Vertebrates -- Evolution.;""Vertebrates -- Molecular genetics."";""Cyclostomata (Bryozoa) -- Evolution."";""Cyclostomata (Bryozoa) -- Molecular genetics."";""Metazoa -- Evolution."";""Metazoa -- Molecular genetics."";""Non-coding RNA."";""MicroRNAs...
Dartmouth Dissertations

The impact of sodium channel isoform expression on cerebellar Purkinje cell development.
Purkinje cells. Sodium channels -- Genetic aspects. Excitation (Physiology). Neurons -- Physiology. Cerebellum -- Physiology. Genetic regulation.
Voltage-dependent sodium channels (Na v ) are critical determinants of the ability of a neuron to generate and propagate action potentials. While a large family of Na v isoforms has been identified, the impact of specific isoforms on the electrical...
Dartmouth Dissertations

New synthetic approaches to chlorins and bacteriochlorins.
Pyrroles -- Synthesis. Porphyrins -- Synthesis.
Naturally occurring macrocyclic tetrapyrroles of the chlorin and bacteriochlorin classes play important roles in essential biological processes, including photosynthesis and nitrogen cycling. The chromophores also show promise in various...
Dartmouth Dissertations

Engineering new tools for targeted drug discovery : design and development of soluble, screenable mimics for challenging proteins / by Chirstopher O. Audu.
The design and synthesis of biomimetic receptor systems capable of binding a target molecule with similar affinities and specificities to their natural counterparts, which are often difficult to obtain in large quantities, has long been a goal of...
Dartmouth Dissertations

Webster Daniel Anniversary 100th
Webster Daniel Anniversary 100th
Webster Daniel Anniversary 100th; speakers at the Daniel Webster Services, Marshfield, October 24, 1952; left to right: President John Sloan Dickey, Dartmouth; President Samuel Sears, Massachusetts Bar Association; Senator Leverett Saltonstall;...
Dartmouth College Photographic Files

Webster Daniel Anniversary 100th
Webster Daniel Anniversary 100th
Webster Daniel Anniversary 100th; Webster Anniversary at Marshfield; October 24, 1952; Daniel Webster, 1782-1852; He belongs to the Nation whose union, rock-ribbed, he so largely wrought. Beloved son, Class of 1801, of the College he loved, his...
Dartmouth College Photographic Files

Webster Daniel Anniversary 100th
Webster Daniel Anniversary 100th
Webster Daniel Anniversary 100th; At Daniel Webster Services; October, 1952; Marshfield, Massachusetts; President Dickey; Samuel Sears; Senator Saltonstall; Commander David F. Toomey; Massachusetts Department Veterans of Foreign Wars; Daniel...
Dartmouth College Photographic Files

Webster Daniel Anniversary 100th
Webster Daniel Anniversary 100th
Webster Daniel Anniversary 100th; Winslow cemetary showing memorial tablet presented by? or to? Daniel Webster ; October 24, 1952; Daniel Webster, 1782-1852; He belongs to the Nation whose union, rock-ribbed, he so largely wrought. Beloved son,...
Dartmouth College Photographic Files

Webster Daniel Residences, Relics, Etc. II
Webster Daniel Residences, Relics, Etc. II
Webster Daniel Residences, Relics, Etc. II; Daniel Webster 1782-1852; He belongs to the Nation whose union, rock-ribbed, he so largely wrought. Beloved son, Class of 1801, of the College he loved, his defense of her independence in the Dartmouth...
Dartmouth College Photographic Files

Webster Daniel Family
Webster Daniel Family
Webster Daniel Family; Mr. Lewis A. Armistead, great great grandson of Daniel Webster through Daniel's daughter Julia who was his only daughter to survive to adulthood; C. F. Foling? Genealogy of D. Webster Family; Webster Anniversary, October 24,...
Dartmouth College Photographic Files

Webster Daniel Anniversary 100th
Webster Daniel Anniversary 100th
Webster Daniel Anniversary 100th; Daniel Webster, 1782-1852; He belongs to the Nation whose union, rock-ribbed, he so largely wrought. Beloved son, Class of 1801, of the College he loved, his defense of her independence in the Dartmouth College...
Dartmouth College Photographic Files

Synthetic studies of Munchnone reactivity and applications and the total synthesis of cyclopenta[B]indole natural products / by Justin M. Lopchuk.
Chapter 1: Munchnones and mesoionic heterocycles The reactivity, regioselectivity, and synthetic applications of munchnones (1,3-oxazolium-5-olates) is a common theme which runs through Chapters 2-5. The definition, structure, and reactivity of...
Dartmouth Dissertations

Combined MRI and near-infrared spectroscopy for increased specificity of breast cancer imaging / by Michael A. Mastanduno.
A yearly breast contrast-MR scan is recommended to high-risk women because of MR's high sensitivity to breast tumors. However, breast contrast-MR yields a high number of false positives that lead to expensive and sometimes unnecessary biopsy...
Dartmouth Dissertations

Acquisition and registration of 3D optical surface scanning, MRI, and microwave tomographic imaging for improved clinical breast imaging and surgical planning / by Matthew John Pallone.
Continual improvements to clinical breast imaging technologies have led to ever earlier detections and increasingly accurate localizations of female breast cancers. While these advancements have certainly improved the prognoses of many patients,...
Dartmouth Dissertations

Understanding the vulnerabilities of tumors : a network-based approach to drug target discovery / by Nadia M. Penrod.
The demand for novel molecularly targeted drugs will continue to rise as we make progress toward personalizing cancer treatments to the molecular signatures of individual tumors. While the collection and analysis of genomic data has become routine,...
Dartmouth Dissertations

Advancement of magnetic resonance poroelastography for applications in brain imaging / by Adam J. Pattison.
Brain tissue mechanics are an important biomarker for neurological disorders, yet methods to obtain tissue information yield inconsistent conclusions. These techniques can be invasive or require excised tissue, where tissue function is altered from...
Dartmouth Dissertations

Magnetic nanoparticle hyperthermia as an adjuvant cancer therapy with chemotherapy / by Alicia Ailie Petryk.
Magnetic nanoparticle-based hyperthermia for cancer treatment is a promising technology, particularly when applied as part of an adjuvant strategy with established cancer therapies (chemotherapy, radiation and surgery). In Europe, early clinical...
Dartmouth Dissertations

Estradiol regulation of innate immune protection in the human female reproductive tract / by Mickey Vinay Patel.
Estradiol is a key regulator of immune protection in the female reproductive tract (FRT). Its concentration varies during the menstrual cycle, leading to changes in innate immune protection. In this thesis, I demonstrate the multiple levels at...
Dartmouth Dissertations

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