Neonatal infections -- Prevention. Nosocomial infections -- Prevention. Neonatal intensive care -- Social aspects. Neonatal intensive care -- Psychological aspects.
Statement of the problem. Nosocomial bloodstream infections (NBSIs) are a significant source of morbidity and mortality for the very low birth weight babies (VLBW) in neonatal intensive care units (NICUs). Efforts to reduce the rates of infection...
We present aligned hierarchies, a novel solution to the dimension reduction problem, representing high-dimensional and noisy sequential data as a low-dimensional object that encodes relevant information. In this thesis, we motivate our presentation...
The circadian clock of the filamentous fungus, Neurospora crassa, consists of a frequency-white-collar ( frq-wc ) based and transcription-translation-derived oscillator. Negative feedback regulation is essential for the oscillatory process, in...
As humans we create goals and strive toward ideals, engaging in a constant endeavor to better ourselves or maintain our success. Whether goals are distant hopes for the future, or small steps of change, success requires some control over...
Magnetic nanoparticles are promising candidates for use in biomedical applications as remote sensors of biophysical properties, thermal therapy agents, and detectors of specific biomolecules. Many approaches have been used to model magnetic...
The brain is a vastly interconnected information processing network. In humans, this network supports the rich mental space at the root of the imagination and enables many flexible cognitive abilities such as scientific and artistic creativity. How...
One of the most distinctive aspects of humans as a species is our propensity to form complex social networks made up of intense, non-reproductive bonds with non-kin. Navigating these networks presents a considerable cognitive challenge that is...
Neuroanatomical studies have defined two relatively separate corticohippocampal processing streams that contribute substantially to medial temporal lobe function. Among the cortical regions providing significant input to these processing streams is...
Hematopoietic stem cells (HSCs) balance self-renewal with the continuous production of the suitable numbers of lineage-restricted progenitor cells. In this work we demonstrate that the Mixed lineage leukemia 1 (Mll1) gene is essential for this...
Van Allen radiation belts -- Mathematical models. ; Magnetosphere -- Mathematical models. ; Magnetohydrodynamics -- Mathematical models.
The physics of geomagnetically-trapped radiation has been a topic of interest since the discovery of the Van Allen belts in 1958. As the energetic particles comprising these belts can pose a hazard to human activity in space, considerable effort...
2-D and 3-D woven composites are becoming materials of choice for the forming of structural parts for an ever-increasing range of industries from infrastructure to aerospace. Research has shown that for a wide range of structural composites, in...
Rhizobium -- Physiology. Rhizobium -- Genetics. Plants -- Effect of iron on.
Iron is essential in the agriculturally important symbiosis between Bradyrhizobium japonicum and soybean. Studying iron uptake in B. japonicum presents unique challenges in that the organism is found in two very different environments, free living...
Cholesterol is essential for the survival of all mammalian cells. Mammalian cells obtain cholesterol via two pathways: it can be endogenously synthesized in the endoplasmic reticulum, or it can be obtained from exogenous sources, mainly through the...
For a local field K, we study the affine buildings Ξ n and Δ n naturally associated to SL n ( K ) and Sp n ( K ), respectively. Since Sp n ( K ) is a subgroup of SL 2 n ( K ), we investigate properties of a natural embedding of Δ n in Ξ 2 n ....
Multisensor data fusion. Sensor networks. Plumes (Fluid dynamics). Automatic tracking. Signal processing -- Digital techniques -- Mathematics.
The work in this thesis deals with a novel approach for detecting and tracking chemical plumes in distributed sensor networks. The ultimate objective is solving the inverse location problem: given unknown sources released at unknown times, the...
Successfully navigating our social world requires the ability to understand the facial expressions of others. Indeed, facial expressions provide information about the emotions and intentions of others. While some expressions provide clear...
G proteins -- Receptors. Cardiovascular system -- Diseases -- Genetic aspects. Medical Term Receptors, G-Protein-Coupled -- genetics.
Single-nucleotide polymorphisms (SNPs), particularly non-synonymous variants, provide opportunities for deciphering pathophysiological protein influence. An ideal group for realizing these opportunities is the GPCR-superfamily. Principles from...
Bioinorganic chemistry, a discipline that bridges chemistry and biology, has become increasingly popular as new techniques and analytical methods have emerged to study metals in biological systems. One such technique that has become increasingly...
Psychopaths. Personality and emotions. Emotions and cognition.
Research investigating clinical and criminal psychopaths is quite extensive. Though it has evolved in terminology over the years, the basic premise and description of psychopathy has maintained deficits associated with emotional interpretation and...
Oligomers -- Structure -- Mathematical models. Nuclear magnetic resonance spectroscopy.
Medical Term: Nuclear Magnetic Resonance, Biomolecular.
Protein complexes play vital roles in the fundamental processes of life. In particular, homo-oligomers are involved in cell signaling, regulation, and transport. To make detailed studies of these symmetric proteins, they need to be discovered, and...
Goldman and Turaev constructed a Lie bialgebra structure on the free Z-module generated by free homotopy classes of loops on an oriented surface. Turaev conjectured that the cobracket of A is zero if and only if A is a power of a simple class. Chas...
Numerical modeling of the global heliosphere provides key insights into the physics of the outer heliosphere. The solar wind data utilized by these models impacts their accuracy and should be as close as possible to the actual solar wind. Ideally,...
In this thesis, the dynamics of long-lived, time-dependent, coherent field configurations, known as oscillons, are investigated in the presence of an expanding background. In a (1+1)-dimensional expanding spacetime, scalar-field oscillon lifetimes...