Ataxia telangiectasia -- Molecular aspects.
DNA damage.
Cell cycle -- Regulation.
Antineoplastic agents.
Cancer cells -- Growth -- Regulation.
Medical Term Cell cycle proteins.
DNA can be damaged by many endogenous and exogenous factors. In response to DNA damage, cells activate cell cycle checkpoints to stop the cell cycle and allow time for repair of the damage. Defects in these pathways allow replication to continue...
Most of the cells that die during the development of a C. elegans hermaphrodite do so within 30 min after being generated. In these cells, the pro-caspase proCED-3 is inherited from progenitors and the transcriptional upregulation of the BH3-only...
Loss of vascular smooth muscle cell function is a hallmark of vascular disease. Vascular smooth muscle cells become increasingly resistant to phenotypic modulation, apoptotic and senescent. Sirtuin 1 (SirT1) is a deactylase that regulates...
During our fieldwork with real-world organizations---including those in Public Key Infrastructure (PKI), network configuration management, and the electrical power grid---we repeatedly noticed that security policies and related security artifacts...
An important mode of stabilization of cations in biochemical reactions is interaction with the π systems-of aromatic residues. As part of an investigation of the interaction of carbocations with aromatic π systems, a study of various model...
Human epidemiological and animal studies have associated inhalation of nickel dusts with increased incidence of pulmonary fibrosis. The current studies examined the hypothesis that nickel promotes pulmonary fibrosis by inhibiting fibrinolysis and...
GABA -- Receptors. ; GABA -- Physiological effect. ; Sexual behavior in animals. ; Hypothalamus -- Physiology.
The overall goal of this research has been to investigate sex-specific and region-specific differences in the function of the γ-aminobutyric acid type A (GABA[subscript A]) receptor in two regions of the brain which are essential for the...