Aneuploidy is the leading cause of pregnancy loss and birth defects in humans. At least 5% of all recognized pregnancies are aneuploid. Maternal meiosis is especially error-prone and the rate of chromosome missegregation increases exponentially...
'Orthogonal modular forms are algebraic modular forms arising from lattices in quadratic spaces. In this thesis, we define orthogonal modular forms, establish their basic properties, and then apply them to a case of ternary quadratic spaces to...
Proper regulation of chromosome segregation during cell division is essential to prevent aneuploidy. During mitosis as well as meiosis, the cohesin complex physically holds sister chromatids together and is necessary for proper segregation of...
Home care services -- Utilization -- New Hampshire. Home care services -- New Hampshire -- Evaluation. Maternal health services -- Utilization -- New Hampshire. Infant health services -- Utilization -- New Hampshire. Prenatal care -- Utilization --...
Research objective . Research suggests that home visiting services can have a significant impact on pregnancy outcomes, child health and development, parenting and maternal life course. The effect of home visiting on utilization of health services...
Electronic data processing -- Distributed processing. ; Computer network architectures. ; Programming languages (Electronic computers) -- Semantics. ; Database management.
I tackle the problem of naming and sharing resources across administrative boundaries. Conventional systems manifest the hierarchy of typical administrative structure in the structure of their own mechanism. While natural for communication that...
Coding theory. Characters of groups. Error-correcting codes (Information theory). Polynomials.
We introduce vector-valued character theory, a higher dimensional generalization of character theory. We then use vector-valued characters to extend the MacWilliams equivalence theorem for linear codes to a class of additive codes, called...
For a local field K, we study the affine buildings Îž n and Î” n naturally associated to SL n ( K ) and Sp n ( K ), respectively. Since Sp n ( K ) is a subgroup of SL 2 n ( K ), we investigate properties of a natural embedding of Î” n in Îž 2 n ....
Accurate chromosome segregation in human oocytes requires that meiotic sister chromatid cohesion remain intact for decades and work in model organisms indicates that deterioration of meiotic cohesion over time may be a major determinant of...
Thermodynamics, and the classic balance between entropy and enthalpy, provides a proverbial zoo of exotic phase behaviour that chemists can harness to create new materials out of simple liquids and polymers. The diversity of self-assembling...
Constructibility (Set theory). Trees (Graph theory).
This thesis investigates possible initial segments of the degrees of constructibility. Specifically, we completely characterize the structure of degrees in generic extensions of the constructible universe L via forcing with Souslin trees. Then we...
Epilepsy is associated with cognitive impairments which often manifest as a higher prevalence of memory impairments. Memory impairments in patients with epilepsy may persist even with sufficient control of seizures, suggesting other factors may...
This thesis centers around a generalization of the classical discrete Fourier transform. We first present a general diagrammatic approach to the construction of efficient algorithms for computing the Fourier transform of a function on a finite...
Identifying the determinants of reproductive success in small-scale societies is critical for understanding how natural selection has shaped human evolution and behavior. The available evidence suggests that status-accruing behaviors such as...
The performance of machine learning algorithms largely depends on data representation. As a critical step in machine learning, representation learning (feature learning) learns a transformation of training data to give a new representation that can...
In this thesis, we study the dynamics of magnetic flows on compact nilmanifolds. Magnetic flows are generalizations of geodesic flows. They model the motion of a particle of unit mass and unit charge in a smooth manifold M in the presence of a...
This thesis is divided into 2 parts. In the first part of the thesis, we describe a software based approach to speeding up the Magnetic Resonance Imaging modality. In the second part of the thesis, we describe Significance Tree Quantization, which...
Information resources management -- Mathematical models. ; Database management -- Methodology. ; Change. ; World Wide Web.
Many modern information management tasks consist of an observer that must maintain current knowledge of a collection of changing information. The goal of this observer is to maintain acceptably accurate state estimates given limited observation...
This thesis describes a new synthesis of substituted (3H)-1,2-dithiole-3-thiones (dithiolethiones) from readily available starting materials. Dithiolethiones have a wide variety of industrial and pharmaceutical applications. These include use as...
Geomagnetic micropulsations. ; Magnetosphere. ; Cosmic magnetic fields -- Measurement.
A study of magnetospheric pulsations is presented in three parts. The first consists of a statistical survey using data from the AMPTE/IRM satellite. A number of conclusions are drawn from the study. Evidence is provided that supports the theory...
DC-to-DC converters -- Design and construction. Electric inductors -- Design and construction. Thin film devices -- Design and construction. Microprocessors -- Power supply. Microfabrication. Transients (Dynamics).
Friction severely limits performance in precise positioning systems. This thesis investigates one possible approach to counter friction related performance losses, friction cancellation. In this method a friction observer is used to estimate...
Our conscious experience of memory often includes reconstuctions of the past in order to fill the gaps of forgotten events and details. The goal of this thesis is to use the tools of cognitive neuroscience to better understand the cognitive and...
We consider a problem of information overload: the conflict between vast amounts of data available in electronic form and inadequate tools for finding relevant information. To alleviate this problem we look at the information organization:...
Multimedia systems -- Mathematical models. ; Information storage and retrieval systems. ; Machinery -- Alignment.
This thesis introduces multiple media correlation, a new technology for the automatic alignment of multiple media objects such as text, audio, and video. This research began with the question: what can be learned when multiple multimedia components...
Human behavior -- Mathematical models. ; Web usage mining. ; Internet users.
Whom we e-mail, where we browse, what we purchase, and the things we search for on the World Wide Web all leave identifiable traces of who we are as individuals. In today's technology focused landscape, cyberspace represents the new environment in...
A hallmark of apoptosis is internucleosomal DNA fragmentation catalyzed by an endogenous endonuclease. Many laboratories have implicated the activation of Ca2+/Mg2+-dependent endonucleases or the acid-dependent deoxyribonucleases, (DNase II),...
Accurate chromosome segregation during mitosis and meiosis requires that sister-chromatid cohesion hold sisters together until the appropriate time. In addition, meiotic cohesion is necessary for normal synaptonemal complex (SC) and homologous...