Dartmouth Digital Library Program

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Reactor design considerations for the conversion of particulate biomass to ethanol.
Bioreactors -- Design and construction. Alcohol as fuel. Biomass energy.
Dartmouth Dissertations

Characterization and rescue of a Drosophila model of prion disease; and The role of carcinine in signaling at the Drosophila photoreceptor synapse.
Drosophila melanogaster -- Genetic aspects. Prion diseases. Neurotransmitters. Photoreceptors.
Drosophila melanogaster is a model organism often used when studying the complex processes of neuronal signaling and neurodegeneration. The short life cycle, malleable genetics, amenability to in vivo electrophysiological assays and sensitivity to...
Dartmouth Dissertations

Design of governmental policies for oil production rates and oil income spending: a long-term perspective.
Petroleum industry and trade -- Norway. ; Government spending policy -- Norway. ; Petroleum -- Rates -- Mathematical models.
Dartmouth Dissertations

Conversion of paper sludge to ethanol and analysis of selection based strain improvement for recombinant Saccharomyces cerevisiae expressing saccharolytic enzymes through continuous culture.
Cellulase -- Biotechnology. ; Hydrolysis. ; Paper industry -- Technological innovations. ; Biomass energy -- Economic aspects. ; Saccharomyces cerevisiae -- Genetics. ; Enzymes -- Industrial applications.
Paper sludge is the largest solid waste stream produced by pulp and paper industry, and is also an attractive feedstock for emergent technologies based on processing of cellulosic biomass featuring enzymatic hydrolysis. This study focuses on...
Dartmouth Dissertations

Cellulosic biomass to ethanol: kinetic modeling, scale up, and reactor design.
Bioreactors -- Design and construction. ; Biochemical engineering -- Computer simulation. ; Mixing. ; Fermentation. ; Alcohol as fuel. ; Biomass energy.
Biological conversion of biomass to fuels and chemicals offers recognized benefits. The absence of systematic methodologies for scaling up such conversion is an important issue related to realizing these benefits. This thesis addresses this scale...
Dartmouth Dissertations

Investigation of the requirements for transitional endoplasmic reticulum (tER) site structure and function in Saccharomyces cerevisiae.
Endoplasmic reticulum.; Membrane proteins -- Physiological transport. ; Coated vesicles. ; Golgi apparatus. ; Saccharomyces cerevisiae -- Molecular aspects. ; Phospholipids -- Physiological effect. ; Saccharomyces cerevisiae Proteins. ; COP-Coated...
Eukaryotic cells contain distinct membrane-bound organelles that house sets of specialized metabolic reactions. The network of controlled communications between organelles is known as the secretory pathway. Transport of proteins and lipids between...
Dartmouth Dissertations

Metabolic Engineering of Thermoanaerobacterium saccharolyticum and Thermoanaerobacterium thermosaccharolyticum for n-butanol production / by Ashwini Bhandiwad.
The increasing demand for transportation energy coupled with the need to reduce carbon emissions for a sustainable future are driving forces to develop alternative fuels. One promising alternative to petroleum is conversion of lignocellulosic...
Dartmouth Dissertations

Production of ethanol from lignocellulosic materials using thermophilic bacteria.
Alcohol -- Production methods. ; Lignocellulose. ; Thermophilic bacteria.
Dartmouth Dissertations

Heterogeneous dissolution fundamentals in water only pretreatment of biomass.
Biomass conversion. Hemicellulose -- Biodegradation. Hydrolysis. Sugar -- Solubility. Xylans -- Solubility.
This thesis characterized the solubilities of sugar monomers and xylooligomers in water and explored the potential role of solubility for pretreatment of cellulosic Biomass by hemicellulose hydrolysis in only water. A novel apparatus was developed...
Dartmouth Dissertations

Brain repair after trauma : birth and migration of immature neurons after focal traumatic brain injury in piglets and human children / by Sabrina Rose Taylor.
Traumatic brain injury (TBI) is the leading cause of acquired disability in children, yet innate repair mechanisms are incompletely understood. A possible innate mechanism to repair injury after insult is neurogenesis - the birth, migration,...
Dartmouth Dissertations

Metabolic engineering of high yield ethanol production in Thermoanaerobacterium saccharolyticum.
Microbial metabolism. ; Microbial genetic engineering. ; Thermophilic bacteria -- Genetic engineering. ; Anaerobic bacteria -- Genetic engineering.
A sustainable energy future is critical for environmental and strategic reasons. One alternative to petroleum used for transportation is ethanol derived from cellulosic biomass. The major barrier for biomass conversion is a cost effective method...
Dartmouth Dissertations

Metal distribution in Arabidopsis.
Arabidopsis -- Effect of metals on. ; Zinc -- Physiological transport. ; Iron -- Physiological transport. ; Plants -- Effect of iron on. ; Plants -- Effect of zinc on.
Iron and zinc deficiency commonly limit plant growth and crop yields. Furthermore, deficiencies in both of these micronutrients are common throughout the world, particularly in developing countries where people may only consume simple diets...
Dartmouth Dissertations

The use of computer models to capture, understand and control dynamic brain processes.
Brain -- Physiology -- Mathematical models. Brain stem -- Effect of chemicals on. Basal ganglia -- Physiology.
Understanding how the brain works remains one of the toughest problems in science, despite the progress in scientific technology available for its study. The difficulty lies in the fact that the brain is a dynamic system, while the body of facts...
Dartmouth Dissertations

Enzymatic hydrolysis of cellulosic biomass solids prepared by leading pretreatments and identification of key features governing performance.
Cellulase -- Absorption and adsorption. Enzymes -- Biotechnology. Cellulose -- Biodegradation. Lignocellulose -- Biotechnology. Biomass conversion. Hydrolysis. Corn stover. Poplar -- Biotechnology.
Prior to biological conversion of lignocellulosic biomass, natural barriers to efficient enzymatic hydrolysis must be overcome, and a few pretreatment technologies effectively accomplish this job with chemicals. Although several factors are...
Dartmouth Dissertations

Natural and engineered metabolism of Thermoanaerobacterium saccharolyticum during growth on plant derived mono- and polysaccharides / by Devin Hedley Currie.
Many microbes thrive in conditions that would be detrimental to human life. These microorganisms have been dubbed extremophiles. Of these, members of a subcategory, termed thermophiles, grow optimally above 45°C. Thermoanaerobacterium...
Dartmouth Dissertations

Simultaneous saccharification and co-fermentation of paper sludge.
Cellulose -- Biodegradation. Zymomonas mobilis -- Biotechnology. Saccharomyces cerevisiae -- Biotechnology. Fermentation. Hydrolysis. Biomass conversion -- Mathematical models.
Production of fuel ethanol from cellulosic materials is a potentially attractive way to meet sustainability, energy security, and environmental goals. However, the high cost of processing using current technology has thus far prevented...
Dartmouth Dissertations

Mapping ultramafic rocks by computer analysis of digital LANDSAT data.
Rocks Ultrabasic. ; Geology -- Data processing.
Dartmouth Dissertations

In vivo degradation in modern orthopaedic UHMWPE bearings and structural characterization of a novel alternative UHMWPE material / by Steven D. Reinitz.
Ultra-high molecular weight polyethylene (UHMWPE) remains the most common bearing material for total joint arthroplasty. Advances in radiation cross-linking and other post-consolidation treatments have led to a rapid differentiation of polyethylene...
Dartmouth Dissertations

Data-based computational support of risky decision making on sustainable environmental management / by Peng Ding.
It is never an easy task to make reasonable decisions on how people should act to preserve natural resources and to have various stakeholders agree with such decisions. This difficulty arises for a number of reasons, including: (1) the existence of...
Dartmouth Dissertations

Expression and recovery of recombinant proteins in a novel high cell density prokaryotic system based on Ralstonia eutropha.
Ralstonia -- Biotechnology. Microbial biotechnology. Industrial microbiology. Recombinant proteins -- Synthesis. Recombinant Proteins -- Biosynthesis.
Escherichia coli is the standard host for recombinant protein expression in bacteria, but suffers from some limitations (e.g. poor fermentation performance, inclusion body formation and proteolysis). A novel recombinant protein expression system,...
Dartmouth Dissertations

The role of government in encouraging the market penetration of newly-emerging energy technologies: a parabolic trough case study.
Solar energy industries -- United States.; Solar collectors -- United States. ; Subsidies -- United States.
Dartmouth Dissertations

Consolidated bioprocessing and liquid hot water pretreatment for the production of ethanol from cellulosic substrates.
Cellulose -- Biotechnology. ; Alcohol as fuel. ; Compressed water.
Dartmouth Dissertations

Soil biogeochemistry in temperate and arctic ecosystems : human disturbances to a critical carbon pool / by Chelsea L. Petrenko
I investigated the effects of two contemporary disturbances to soil systems: forest clearing in the northeastern U.S. and climate-driven plant succession in the Arctic. To test the effects of clear-cutting forests on mineral soil carbon (C)...
Dartmouth Dissertations

Metabolic engineering of catabolic product metabolism in thermophilic bacteria.
Thermophilic bacteria -- Metabolism. Thermophilic bacteria -- Genetics. Thermophilic bacteria -- Biotechnology. Cells
Metabolic engineering of the catabolic end-product metabolism of Thermoanaerobacterium saccharolyticum was initiated. T. saccharolyticum is an anaerobic, thermophilic bacterium that utilizes xylans and xylose, the second most prominent sugar after...
Dartmouth Dissertations

Hydrothermal pretreatment of cellulosic biomass for bioconversion to ethanol.
Alcohol as fuel. ; Cellulose -- Biotechnology. ; Hot water. ; Steam. ; Biomass energy.
Dartmouth Dissertations

Physiology and kinetics of cellulose fermentation by Clostridium thermocellum / by Evert K. Holwerda
Cellulolytic microorganisms hold promise for industrially applied microbial cellulose utilization in the generation biofuels from renewable resources. Consolidated bioprocessing (CBP), a one-step process combining cellulase production, cellulose...
Dartmouth Dissertations

Fundamentals of microbial cellulose utilization by the thermophilic bacterium Clostridium thermocellum.
Clostridium -- Biotechnology. ; Cellulose -- Biodegradation. ; Thermophilic bacteria. ; Hydrolysis.
The thermophilic anaerobic bacterium Clostridium thermocellum has attracted researchers attention because of its potential industrial application and high cellulose hydrolysis rates. This study focuses on the physiological fundamentals of C....
Dartmouth Dissertations

Gene transfer in thermophilic Clostridium.
Clostridium -- Biotechnology. ; Genetic transformation. ; Restriction enzymes DNA.
Dartmouth Dissertations

Kinetics of acid hydrolysis of hardwood in a continuous plug flow reactor.
Fluid mechanics. ; Wood. ; Hydrolysis.
Dartmouth Dissertations

Partial acid hydrolysis pretreatment for enzymatic hydrolysis of cellulose : a process development study for ethanol production.
Cellulose. ; Hydrolysis. ; Refuse as fuel.
Dartmouth Dissertations

Design and control of high-density DC-DC converters for cell balancing and low-voltage power delivery applications / by Christopher Schaef
In a variety of applications spanning mobile devices, performance computing, and even renewable energy and automotive, power management and power delivery are an increasing bottleneck in reducing size and cost, improving reliability, and even...
Dartmouth Dissertations

OPEC1 : a long-term model of world oil supplies and prices.
Organization of Petroleum Exporting Countries. ; Petroleum industry and trade -- Mathematical models.
Dartmouth Dissertations

Evaluation and engineering of Saccharomyces cerevisiae for cellulase expression and growth on insoluble cellulose.
Saccharomyces cerevisiae -- Genetics. Cellulase -- Biotechnology. Cellulose -- Biotechnology. Biomass conversion -- Technological innovations.
Dartmouth Dissertations

Investigating the scale-up of anaerobic soluble sugar fermentations for large-scale ethanol production.
Alcohol -- Synthesis -- Computer simulation. Corn -- Biotechnology. Fermentation -- Computer simulation. Alcohol as fuel. Computational fluid dynamics.
Renewable energy sources are becoming increasingly important as sustainable alternatives to fossil fuels. One of these renewable sources, cellulosic biomass, is a relatively inexpensive and abundant resource that can be converted into liquid fuels...
Dartmouth Dissertations