Dartmouth Digital Library Program

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The role of nongeometric information in spatial language.
Space and time in language. ; Space perception. ; Figure-ground perception. ; Psycholinguistics.
Across languages, there exists a relatively small number of spatial prepositions. These terms are used to express the infinite number of possible spatial locations of an unlimited number of different entities in the environment. Previous research...
Dartmouth Dissertations

Delayed visual feedback and visual-motor control.
Feedback (Psychology); Visual evoked response. Motor ability.
Dartmouth Dissertations

Regeneration studies of a single indentifiable motoneuron in the crayfish Procambarus Clarkii.
Motor neurons. ; Nervous system -- Regeneration. ; Crayfish.
Dartmouth Dissertations

Linking Atlantic salmon (Salmo salar) survival with their habitat using environmental tracers.
Atlantic salmon -- Ecology. ; Atlantic salmon -- Habitat. ; Atlantic salmon -- Food. ; Radioactive tracers in ecology. ; Stable isotopes in ecological research. ; Strontium -- Isotopes -- Environmental aspects. ; Cesium -- Isotopes -- Environmental...
Dartmouth Dissertations

Sounding rocket based investigations of HF waves in the auroral ionosphere.
Ionospheric radio wave propagation -- Observations. ; Auroras -- Alaska -- Observations. ; Sounding rockets -- Observations.
Dartmouth Dissertations

Effects of anabolic androgenic steroids on GABAA receptor function and expression.
Anabolic steroids -- Physiological effect. ; Androgens -- Physiological effect. ; GABA -- Receptors. ; GABA -- Physiological effect. ; Neurotransmitter receptors. ; Brain -- Physiology. ; Receptors GABA-A -- drug effects.
Dartmouth Dissertations

Burial and contact metamorphism in the Mancos shale.
Shale -- Rocky Mountains. ; Metamorphism (Geology).
Dartmouth Dissertations

The role of p53 in retinoic acid-induced differentiation of human germ cell tumors.
p53 antioncogene -- Regulation. ; Retinoids -- Physiological effect. ; Retinoids -- Receptors. ; Cell differentiation -- Molecular aspects. ; Genetic transcription -- Regulation. ; Germ cells -- Tumors. ; Receptors.
The retinoids exert potent growth and differentiation effects on normal, embryonic and neoplastic cells. Although retinoids are known to regulate gene transcription through activation of retinoid receptors, the direct target genes of retinoid...
Dartmouth Dissertations

Characterization of molecular subsets of scleroderma using pathway analysis and animal models.
Scleroderma (Disease) -- Genetic aspects. Scleroderma (Disease) -- Molecular aspects. Cytokines -- Pathophysiology. Gene expression. Cellular signal transduction.
Scleroderma (systemic sclerosis; SSc) is a devastating autoimmune disease of unknown etiology for which there is no cure, and no truly effective therapies available. Immune dysfunction, fibrosis and vasculopathy are the three major features of the...
Dartmouth Dissertations

The development of magnetic susceptibility weighted magnetoencephalography
Magnetoencephalography -- Technique.; Magnetic susceptibility.
The measurement of human brain function is the goal of many noninvasive medical imaging modalities. Two sources of physiological contrast are commonly targeted to achieve this goal. The most direct approach to measuring neuronal activity is with...
Dartmouth Dissertations

Addressing and assessing spirituality in primary care medicine.
Medicine -- Religious aspects. Health -- Religious aspects. Spirituality -- Health aspects. Spirituality -- Testing. Primary care (Medicine). Patients -- Religious life.
Background . Although the epidemiology of spirituality/religion is still an emerging field, initial research suggests spirituality may promote better health. Additionally, physician-inquiry about spirituality may enhance the quality and possibly...
Dartmouth Dissertations

The P. aeruginosa CRISPR/Cas system and its role in bacteria-bacteriophage interactions
CRISPR/Cas systems are a diverse family of small RNA pathways that are commonly described as a resistance mechanism to infection by lytic bacteriophage and invasion by conjugative plasmids. In the current work we demonstrate that CRISPR/Cas systems...
Dartmouth Dissertations

Combining biological and statistical learning principles for minimally supervised object recognition / by Ashok Chandrashekar.
Despite great progress in object recognition techniques, there is a mismatch between traditional approaches and the characteristics of real world vision tasks. We highlight in particular, three closely related areas of mismatch: i) recognition...
Dartmouth Dissertations

Synthetic studies of Munchnone reactivity and applications and the total synthesis of cyclopenta[B]indole natural products / by Justin M. Lopchuk.
Chapter 1: Munchnones and mesoionic heterocycles The reactivity, regioselectivity, and synthetic applications of munchnones (1,3-oxazolium-5-olates) is a common theme which runs through Chapters 2-5. The definition, structure, and reactivity of...
Dartmouth Dissertations

Acquisition and registration of 3D optical surface scanning, MRI, and microwave tomographic imaging for improved clinical breast imaging and surgical planning / by Matthew John Pallone.
Continual improvements to clinical breast imaging technologies have led to ever earlier detections and increasingly accurate localizations of female breast cancers. While these advancements have certainly improved the prognoses of many patients,...
Dartmouth Dissertations

Understanding the vulnerabilities of tumors : a network-based approach to drug target discovery / by Nadia M. Penrod.
The demand for novel molecularly targeted drugs will continue to rise as we make progress toward personalizing cancer treatments to the molecular signatures of individual tumors. While the collection and analysis of genomic data has become routine,...
Dartmouth Dissertations

Advancement of magnetic resonance poroelastography for applications in brain imaging / by Adam J. Pattison.
Brain tissue mechanics are an important biomarker for neurological disorders, yet methods to obtain tissue information yield inconsistent conclusions. These techniques can be invasive or require excised tissue, where tissue function is altered from...
Dartmouth Dissertations

Sampling for complexity in rendering / by Jiawei Ou.
As the visual effect and movie industries are striving for realism and high fidelity images, physically based lighting, global illumination, realistic materials, and highly tessellated geometry are gradually accepted and used in movie and game...
Dartmouth Dissertations

Estradiol regulation of innate immune protection in the human female reproductive tract / by Mickey Vinay Patel.
Estradiol is a key regulator of immune protection in the female reproductive tract (FRT). Its concentration varies during the menstrual cycle, leading to changes in innate immune protection. In this thesis, I demonstrate the multiple levels at...
Dartmouth Dissertations

A computational study of radio relics in galaxy cluster mergers / by Dane Patrick Owen.
Radio relics are extended regions of synchrotron radio emission that have been found in the outskirts of a few dozen galaxy clusters. Relics are often associated with clusters undergoing merger activity. They are not associated optically with a...
Dartmouth Dissertations

Endogenous leukocyte activation by chimeric antigen receptor T cell immunotherapy / by Paul Spear.
Many protocols for adoptive T cell therapy (ACT) include preparative conditioning strategies to deplete host lymphocytes prior to T cell infusion. Total body irradiation and high-dose chemotherapy regimens not only relieve immunosuppression, but...
Dartmouth Dissertations

Using theory to predict phase behaviour in liquids, copolymer melts, and ultrathin polymer films / by Nicholas B. Tito.
Thermodynamics, and the classic balance between entropy and enthalpy, provides a proverbial zoo of exotic phase behaviour that chemists can harness to create new materials out of simple liquids and polymers. The diversity of self-assembling...
Dartmouth Dissertations

Alterations in the production of bacteriochlorophyll a and okenone in purple sulfur bacteria : implications for the interpretaion of their biomarkers / by Derek A. Smith.
Purple sulfur bacteria (PSB) can dominate the nitrogen, carbon, and sulfur cycles in anoxic ecosystems via their anoxygenic photosynthetic metabolisms and are the only producers of the carotenoid, okenone, a biomarker targeted for photic zone...
Dartmouth Dissertations

Security-policy analysis with eXtended unix tools / by Gabriel A. Weaver.
During our fieldwork with real-world organizations---including those in Public Key Infrastructure (PKI), network configuration management, and the electrical power grid---we repeatedly noticed that security policies and related security artifacts...
Dartmouth Dissertations

Noninvasive fluorescence monitoring for functional assessment of murine glioma treatment.
Gliomas -- Immunotherapy -- Evaluation. Fluorescence spectroscopy. Diagnosis.
Molecular optical imaging in vivo has potential for functional assessment of tumor tissue at the cellular and subcellular level. Advances in biological understanding of genomics and proteomics have increased the knowledge of possible cellular...
Dartmouth Dissertations

C.O.A.L.1: a dynamic model for the analysis of United States energy policy.
Energy policy -- United States -- Mathematical models.
Dartmouth Dissertations

A multivariate analysis of self-selection and change due to college experience.
College students -- Psychology. College environment.
Dartmouth Dissertations

Amine catalysis of B-elimination reactions.
Catalysis. Chemical reactions. Amines.
Dartmouth Dissertations

Color centers and thermoluminescence in LiF.
Thermoluminescence. Lithium fluoride.
Dartmouth Dissertations

Effect of vicarious punishment on sharing behavior in children.
Sharing. Child psychology.
Dartmouth Dissertations

Excitatory and inhibitory properties of human facial expressions of emotion.
Facial expression. Emotions.
Dartmouth Dissertations

A psychophysical investigation of cortical cell receptive field organization in the human visual system.
Visual perception. Visual discrimination.
Dartmouth Dissertations

Examining functional variation in oncogene biology : the role of somatic mutations and germline variation on c-Myc and c-Myb / by Scott Andrew Turner.
The identification and characterization of functional genetic variation is essential for future advances in molecular diagnostics, pharmacogenomics, and personalized medicine. Recent attempts at identifying nucleotide level variation (somatic...
Dartmouth Dissertations

A dynamically refocusable sampling infrastructure for 802.11 networks.
Telecommunication -- Traffic -- Measurement -- Statistical methods. IEEE 802.11 (Standard). Universities and colleges -- Computer networks -- New Hampshire -- Hanover -- Case studies.
The edge of the Internet is increasingly wireless. Enterprises large and small, homeowners, and even whole cities have deployed Wi-Fi networks for their users, and many users never need to--or never bother to--use the wired network. With the advent...
Dartmouth Dissertations

Spectroscopic analyses of type Ia supernovae / by Jerod Parrent.
After decades of searching we have yet to find the progenitor systems for type Ia supernovae. In fact most of what we know about this homogeneous class of supernovae is from spectral features associated with the incinerated remains of the C+O white...
Dartmouth Dissertations

Dissecting the heterogeneity of breast tumor subtypes / by Nima Pouladi.
Breast cancer is the most common cancer in women. The discovery of breast tumor subtypes and the subsequent development of treatments aimed at them has allowed a reduction in the mortality of breast cancer. However, tumors with similar...
Dartmouth Dissertations

Access control in and for the real world / by Sara Sinclair.
Access control is a core component of any information-security strategy. Researchers have spent tremendous energy over the past forty years defining abstract access-control models and proving various properties about them. However, surprisingly...
Dartmouth Dissertations

Characterization of an inducible model of a genetic prion disease in Drosophila melanogaster / by Archana Murali.
Prion diseases are progressive disorders that affect the central nervous system leading to memory loss, personality changes, ataxia and neurodegeneration. In humans, these disorders include Creutzfeldt-Jakob disease, kuru and...
Dartmouth Dissertations

Group-aware stream filtering.
Streaming technology (Telecommunications). Computer networks -- Monitoring. Multicasting (Computer networks). Electronic data processing -- Distributed processing.
Recent years have witnessed a new class of monitoring applications that need to continuously collect information from remote data sources. Those data sources, such as web click-streams, stock quotes, and sensor data, are often characterized as...
Dartmouth Dissertations

Microbial mediation of plant-pollinator interactions / by Robert N. Schaeffer II.
Floral nectar of many plant species is prone to colonization by microorganisms. Their presence and metabolism have the potential to modify a suite of traits important for pollinator attraction, including nectar quality and scent. However, studies...
Dartmouth Dissertations

System and methodology for receptor-level fluorescence imaging during surgery / by Kristian Sexton.
Fluorescence molecular imaging will have an important clinical impact in the area of guided oncology surgery, where emerging technologies are poised to provide the surgeon with real-time molecular information to guide resection, using targeted...
Dartmouth Dissertations

SirT1 regulates vascular smooth muscle cell plasticity : implications for age-related cardiovascular disease / by Anne Marie Thompson.
Loss of vascular smooth muscle cell function is a hallmark of vascular disease. Vascular smooth muscle cells become increasingly resistant to phenotypic modulation, apoptotic and senescent. Sirtuin 1 (SirT1) is a deactylase that regulates...
Dartmouth Dissertations

Understanding PDZ affinity and selectivity: all residues considered / by Jeanine F. Amacher.
PDZ protein-protein interaction domains recognize short linear motif (SLiM) sequences typically at the extreme C-terminus of a target protein. These domains often act as scaffolds, connecting target proteins to additional interaction and catalytic...
Dartmouth Dissertations

Combined digital breast tomosynthesis and near-infrared spectral tomography for breast lesion characterization / by Kelly E. Michaelsen.
Annual screening mammograms are recommended for all women above 40 years of age for early detection of breast cancer, and are known to improve cancer mortality rates. However, mammography is hampered by low sensitivity and a high rate of false...
Dartmouth Dissertations

Analytical and computational approaches for quantitative phosphoproteomics / by Jason M. Gilmore.
Protein phosphorylation is an important regulatory mechanism for the control of countless processes in living systems. The delicate management of phosphate attachment to, and removal from, serine, threonine and tyrosine residues in proteins...
Dartmouth Dissertations

The role of DEG/ENaC ion channel subunits in pheromone detection and mating behaviors in Drosophila melanogaster / by Vinoy Vijayan.
Gustatory pheromones regulate mating behaviors in Drosophila melanogaster and represent an important model for understanding how sensory stimuli can drive behavior. However, the genes and cells involved in pheromone detection have remained poorly...
Dartmouth Dissertations

Identification and characterization of signaling pathways underlying the tumorigenic activity of [Delta]Np63[alpha] in breast cancer stem cells / by Amanda Lynn Balboni.
Studies presented in this dissertation focus on the transcriptional targets and cellular functions of [Delta]Np63[alpha], the predominant TP63 isoform expressed in epithelial stem cell compartments. TP63, a member of the p53 family of...
Dartmouth Dissertations

Modflows : methods for studying and managing mesh editing workflows / by Jonathan D. Denning.
At the heart of computer games and computer generated films lies 3D content creation. A student wanting to learn how to create and edit 3D meshes can quickly find thousands of videos explaining the workflow process. These videos are a popular...
Dartmouth Dissertations

Opinion dynamics in social networks / by Qi Gu.
Opinion dynamics is a complex procedure that entails a cognitive process when it deals with how a person integrates influential opinions to form revised opinion. Early research on opinion formation and social influence can be traced back to the...
Dartmouth Dissertations

Towards the experimental verification of macroscopic phenomena in quantum electrodynamics.
Casimir effect. Zero-point field. Electric conductivity. Quantum electrodynamics.
The Casimir force arises from an alteration of boundary condition in vacuum and is often regarded as a manifestation of quantum zero point energy. Considerable progress has been made in the last decade with an impressive achievement of experimental...
Dartmouth Dissertations

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