Numerical modeling of the global heliosphere provides key insights into the physics of the outer heliosphere. The solar wind data utilized by these models impacts their accuracy and should be as close as possible to the actual solar wind. Ideally,...
Cancer Control Program (National Cancer Institute) -- Evaluation. Cancer -- Treatment -- United States -- Evaluation. Cancer -- Patients -- Care -- Evaluation.
Background. Disparities in access to cancer care and cancer-related outcomes have been demonstrated in the U.S. Patterns of access to National Cancer Institute-designated Cancer Centers (NCI-CCs), the most specialized cancer care settings, have not...
Molecular optical imaging in vivo has potential for functional assessment of tumor tissue at the cellular and subcellular level. Advances in biological understanding of genomics and proteomics have increased the knowledge of possible cellular...
Red milkweed beetle. Insects -- Flight. Insects -- Dispersal.
Most detailed studies of insect flight and dispersal have used long flying species as subjects. Little is known of the flight ecology of comparatively short flying species. This thesis reports the findings of a 4 year study of the flight behavior...
Stigma (Social psychology). Aging -- Psychological aspects. Cognition -- Age factors. Older people -- Attitudes.
Extensive research on aging has demonstrated that normal aging debilitates executive function, a system that is critical for regulating stereotypes. However, there is a paucity of research on whether age-related declines to executive function...
This thesis centers around a generalization of the classical discrete Fourier transform. We first present a general diagrammatic approach to the construction of efficient algorithms for computing the Fourier transform of a function on a finite...
Identifying the determinants of reproductive success in small-scale societies is critical for understanding how natural selection has shaped human evolution and behavior. The available evidence suggests that status-accruing behaviors such as...
In this thesis, we study the dynamics of magnetic flows on compact nilmanifolds. Magnetic flows are generalizations of geodesic flows. They model the motion of a particle of unit mass and unit charge in a smooth manifold M in the presence of a...
Spectral theory is the subfield of differential geometry which provided the solution to Kac''s famous question, "Can you hear the shape of a drum?" That is, can we use the Laplace spectrum of a manifold to draw conclusions about its geometry or...
Community health services -- United States -- Evaluation. ; Health care reform -- United States. ; Medical care -- United States -- Evaluation. ; Evidence-based medicine.
There is a long history of attempts to explain why music is perceived as expressive of emotion. Many of the acoustic parameters that are used to communicate emotion in music are also used in human vocal expressions of emotion, suggesting that the...
Hand -- Psychophysiology. Conditioned response. Hand -- Movements. Perceptual-motor processes.
The present studies examine the flexible application of two stimulus-response (SR) mappings to a single set of stimuli. The following questions are addressed: (1) Can dual mapping performance equal single mapping performance (2) Can rapid map...
Social networks -- Mathematical models. Social networks -- Computer simulation. Dynamics. Social sciences -- Network analysis -- Methodology.
Detecting the significance of relationships between people is a complicated and difficult task. This is especially true when these relationships are intermixed with hundreds of different mundane and ordinary interactions that are simply background...
For a local field K, we study the affine buildings Ξ n and Δ n naturally associated to SL n ( K ) and Sp n ( K ), respectively. Since Sp n ( K ) is a subgroup of SL 2 n ( K ), we investigate properties of a natural embedding of Δ n in Ξ 2 n ....
Genetic polymorphisms. Metalloproteinases -- Genetic aspects. Metalloproteinases -- Pathophysiology. Breast -- Cancer -- Genetic aspects. Carcinogenesis.
Extra cellular matrix (ECM) provides structural support for the body and also contributes to cell proliferation and migration. Modification ECM is an important part of normal physiology, and integral to a variety of pathologies including tumor...
Scleroderma (systemic sclerosis; SSc) is a devastating autoimmune disease of unknown etiology for which there is no cure, and no truly effective therapies available. Immune dysfunction, fibrosis and vasculopathy are the three major features of the...
After decades of searching we have yet to find the progenitor systems for type Ia supernovae. In fact most of what we know about this homogeneous class of supernovae is from spectral features associated with the incinerated remains of the C+O white...
Breast cancer is the most common cancer in women. The discovery of breast tumor subtypes and the subsequent development of treatments aimed at them has allowed a reduction in the mortality of breast cancer. However, tumors with similar...
This thesis contains material relating to two separate subjects. The first section determines when the C*-algebra affiliated to a directed graph has continuous trace. We use groupoid methods and the focus is on producing conditions on a graph that...
Studies presented in this dissertation focus on the transcriptional targets and cellular functions of [Delta]Np63[alpha], the predominant TP63 isoform expressed in epithelial stem cell compartments. TP63, a member of the p53 family of...
Epilepsy is associated with cognitive impairments which often manifest as a higher prevalence of memory impairments. Memory impairments in patients with epilepsy may persist even with sufficient control of seizures, suggesting other factors may...
Despite the array of targeted therapeutics that currently exist to combat breast cancer, disease progression leading to metastasis, and tumor recurrence still remains a significant clinical challenge. Efforts to identify novel pathways and...
This thesis constitutes the first steps in the author's program to investigate the question of when a homotopy of 2-cocycles ω = {ω[subscript t]}[subscript t∊[0,1]] on a locally compact Hausdorff groupoid Ɠ induces an isomorphism of the...
In this thesis, we consider several problems relating to cyclic subgroups of the group [mathematical equation]. Each element of [mathematical equation] has a unique representative in one of the two intervals [mathematical equation] and...
G protein coupled receptors (GPCRs) make up somewhere between 30-50% of all current drug targets, yet the structural characterization of these receptors has been moderate at best. Until recently, structural data were almost nonexistent and...
The present thesis is focused on developing a better understanding of factors driving disease biology and overall risk using cancers of the bladder and breast as model systems. As no single approach was likely to unravel the complexities of these...
The Euler '-function and Carmichael -function are extremely important in modern number theory, and much work has been devoted to studying the distribution and arithmetic properties of the values of each function. One interesting unresolved question...
Nutrients play fundamental roles in biological systems, affecting plant growth and quality, community structure, and species interactions. Although the effects of nutrients on primary and secondary production have been well documented, their...
We prove the existence of nontrivial multiparameter isospectral deformations of metrics on the classical compact simple Lie groups SO (n) (n = 9, n ≥11), Spin(n) (n = 9, n ≥11), SU (n) (n ≥7), and Sp (n) (n ≥5). The proof breaks into three...